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However, indicators such as OS and DNA damage provide no information regarding the specific molecular mechanisms underlying the protective effects of wheat germ oil, and few studies have investigated the dose-effect relationship to determine the optimal therapeutic dose and assess the safety profile

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The median OS after CGA treatment was 11.3 months, which showed a prolonged trend as compared with the median OS (5.7 to 7.5 months) for patients in similar stages under standard-of-care therapeutics [302]